| Autor: |
Trujillo, Xóchitl, Mendoza-Cano, Oliver, Ríos-Silva, Mónica, Huerta, Miguel, Guzmán-Esquivel, José, Benites-Godínez, Verónica, Lugo-Radillo, Agustin, Bricio-Barrios, Jaime Alberto, Cárdenas-Rojas, Martha I., Ríos-Bracamontes, Eder Fernando, Ortega-Macías, Vannya Marisol, Ruiz-Montes de Oca, Valeria, Murillo-Zamora, Efrén |
| Předmět: |
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| Zdroj: |
Vaccines; Mar2023, Vol. 11 Issue 3, p626, 7p |
| Abstrakt: |
Background: Repeated SARS-CoV-2 infections are plausible and related published data are scarce. We aimed to identify factors associated with the risk of recurrent (three episodes) laboratory-confirmed symptomatic SARS-CoV-2 infections. Methods: A retrospective cohort study was conducted, and 1,700 healthcare workers were enrolled. We used risk ratios (RR) and 95% confidence intervals (CI) to evaluate the factors associated with symptomatic SARS-CoV-2 infections. Results: We identified 14 participants with recurrent illness episodes. Therefore, the incidence rate was 8.5 per 10,000 person months. In a multiple-model study, vaccinated adults (vs. unvaccinated, RR = 1.05 [1.03–1.06]) and those with a severe first illness episode (vs. mild disease, RR = 1.05 [1.01–1.10]) were at increased risk for repeated symptomatic SARS-CoV-2 reinfections. Increasing age showed a protective effect (per each additional year of age: RR = 0.98 [0.97–0.99]). Conclusions: Our results suggest that recurrent SARS-CoV-2 infections are rare events in adults, and they seem to be determined, partially, by vaccination status and age. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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