The rationale behind serum markers for preterm labor prediction.

Autor: Ali, Alaa Ibrahim, Nori, Wassan, Najma, Mazin A. A.
Předmět:
Zdroj: AIP Conference Proceedings; 2023, Vol. 2591 Issue 1, p1-5, 5p
Abstrakt: Preterm labor is considered a significant cause of perinatal morbidity and mortality; the rate is increasing in developed countries despite the current advances in management. Although several risk factors are present, the ability of preterm labor prediction is still elusive now. Therefore, finding novel biomarkers to identify pregnant women who will subsequently have preterm labor could enable targeted treatments and timely medical intervention for maternal and fetal outcomes improvement. Furthermore, different biochemical markers of a protein source have been found in various body fluids; Saliva, urine, amniotic fluid, blood (serum/plasma), and cervicovaginal fluid; these could reflect different pathophysiological pathways disorders during pregnancy, such as preterm labor. This review highlighted recent advances in the discovery of these current biomarkers. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index