| Autor: |
Ejam, Sura Salman, Saleh, Raed Obaid, Catalan Opulencia, Maria Jade, Najm, Mazin AA, Makhmudova, Aziza, Jalil, Abduladheem Turki, Abdelbasset, Walid Kamal, Al-Gazally, Moaed E, Hammid, Ali Thaeer, Mustafa, Yasser Fakri, Sergeevna, Sergushina Elena, Karampoor, Sajad, Mirzaei, Rasoul |
| Zdroj: |
Future Oncology; Dec2022, Vol. 18 Issue 39, p4415-4442, 28p |
| Abstrakt: |
Cholesterol is an essential lipid that serves several important functions, including maintaining the homeostasis of cells, acting as a precursor to bile acid and steroid hormones and preserving the stability of membrane lipid rafts. 25-hydroxycholesterol (25-HC) is a cholesterol derivative that may be formed from cholesterol. 25-HC is a crucial component in various biological activities, including cholesterol metabolism. In recent years, growing evidence has shown that 25-HC performs a critical function in the etiology of cancer, infectious diseases and autoimmune disorders. This review will summarize the latest findings regarding 25-HC, including its biogenesis, immunomodulatory properties and role in innate/adaptive immunity, inflammation and the development of various types of cancer. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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