Concomitant Primary Hemochromatosis and β-Thalassemia Trait: Iron Depletion by Erythrocytapheresis and Desferrioxamine.

Autor: Cesana, Marina, Mandelli, Clara, Tiribelli, Claudio, Bianchi, Paolo A., Conte, Dario
Předmět:
Zdroj: American Journal of Gastroenterology (Springer Nature); Feb1989, Vol. 84 Issue 2, p150-152, 3p, 2 Charts
Abstrakt: Six men and one woman with mild anemia due to β-thalassemia trait and major iron overload attributable to concomitant primary hemochromatosis were treated by erythrocytapheresis to remove iron, combined with subcutaneous desferrioxamine in the four cases with greater iron load. Depletion was achieved by iron removal of 4.5-15.1 g after 9-24 months' treatment. No side effects were observed, suggesting that such a regimen is effective and safe in this particular subgroup of hemochromatotics. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index