The Role of Platelet-Rich Plasma Injection in the Treatment of Oral Lichen Planus Patients.

Autor: Ibrahim, Samia Ali, Essawy, Abdulla Mohamed, Ahmed, Asmaa Sobhy
Předmět:
Zdroj: Zagazig University Medical Journal; 2023 Supplement, Vol. 29, p330-334, 5p
Abstrakt: Background: Oral lichen planus (OLP) is a mucosal variant of lichen planus disease which generally influences women more than men, it is characterized by more chronic course and potential for multiple recurrence. The aim of the work was to study the effect of intralesional injection of platelet-rich plasma (PRP) in the treatment of OLP. Methods: This therapeutic trial study included 18 patients with OLP collected from the outpatient clinic of Dermatology, Venereology & Andrology Department of Zagazig University Hospitals, each of them had 5 sessions of intralesional PRP injection 2 weeks interval in between. Results: All our patients were greatly improved after PRP sessions. This improvement was evaluated using reticulation/keratosis, erythema, and ulceration (REU) scoring, and photographic assessment. Fortunately, almost all our patients had no side effects to mention after PRP injection, nor any recurrence within 3 months after completing their sessions. Conclusions: PRP injection is an effective method in treatment of OLP. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index