| Autor: |
Ebrahimpour, Shiva, Esmaeili, Abolghasem, Esmaeili, Ali, Sattari, Kimiya, Forouzandeh Hafshejani, Kimiya |
| Předmět: |
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| Zdroj: |
Oral Diseases; Apr2023, Vol. 29 Issue 3, p1356-1366, 11p, 3 Color Photographs, 1 Diagram, 1 Graph |
| Abstrakt: |
Objective: This study aimed to investigate the relationship between different patterns of molar crown loss and the association between symmetrical and asymmetrical shortening molar teeth with memory impairment. Materials and methods: Male Wistar rats were divided into four groups (n = 10) including control, SLM (shortened left molar), SRM (shortened right molar), and SBM (shortened bilateral molar) groups. Morris water maze (MWM) and passive avoidance test (PAT) were performed to assess spatial and fear memory, respectively. Besides, histological assessment of hippocampus and gingival tissues was done. Results: In the MWM test, SBM and SLM groups had higher escape latency over training trials and spent less time in the target quadrant in the probe trial (p < 0.01). In the PAT, step‐through latency was significantly reduced in three groups, and time spent in the dark compartment increased in SBM (p < 0.01) and SLM (p < 0.05) groups. In addition, each teeth shortening group indicated a reduction in density (p < 0.01) and thickness layer (p < 0.05) of pyramidal cells. Gingival was normal after shortening of the molar crown. Conclusions: Different patterns of molar teeth shortening induced learning and memory impairment; however, symmetrical molar teeth shortening has more effects on memory impairment. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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