| Autor: |
Chikunova, Elena I., Kukushkin, Vadim Yu., Dubovtsev, Alexey Yu. |
| Předmět: |
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| Zdroj: |
Green Chemistry; 4/21/2022, Vol. 24 Issue 8, p3314-3320, 7p |
| Abstrakt: |
Gold(I)-catalyzed highly regioselective hydration of alkynylsulfones comprises an efficient 100% atomeconomic route to ß-ketosulfones. The reaction proceeds under mild mercury-free conditions (Ph3PAuNTf2 0.5-5 mol%, THF, rt or 60 °C), it demonstrates a high functional group tolerance (more than 30 examples; yields up to 99%), and can be easily scaled up. The developed hydration methodology was successfully integrated into the one-pot syntheses of valuable heterocycles. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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