| Autor: |
Xiong, Junlong, Cheung, Ying-Kit, Fong, Wing-Ping, Wong, Clarence T. T., Ng, Dennis K. P. |
| Předmět: |
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| Zdroj: |
Chemical Communications; 3/21/2023, Vol. 59 Issue 23, p3471-3474, 4p |
| Abstrakt: |
A β-galactosidase-responsive photosensitiser has been designed and synthesised. It contains a galactosyl substrate, a boron dipyrromethene-based photosensitising unit and a black hole quencher 2 connected via an AB2-type self-immolative linker. This novel photosensitiser can be selectively activated by the senescence-associated β-galactosidase in senescent cells, leading to restoration in fluorescence emission and effective killing of the cells via photodynamic action. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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