| Autor: |
Kochkina, Z. M., Chirkov, S. N. |
| Zdroj: |
Microbiology (00262617); Mar2000, Vol. 69 Issue 2, p208-211, 4p |
| Abstrakt: |
The effect of chitosan derivatives with different degrees of polymerization and deamination, as well as of chitosan 6-O-sulfate and chitosanN-succinate-6-O-sulfate, on the reproduction of coliphages T2 and T7 inEscherichia coli and on the growth of this bacterium was studied. Chitosan derivatives decreased the yield of coliphages and exhibited antibacterial activity. The efficiency of inhibition of viral infection and the antibacterial activity of chitosan were found to be dependent on the degree of its polymerization. At the same time, there was no correlation between the degree of chitosan deamination and the extent of inhibition of viral infection. Anionic chitosan derivatives virtually did not possess antiviral or antibacterial activity. It is assumed that chitosan blocks some stages of phage reproduction. The decrease in the phage-producing ability ofE. coli may also be due to the antibacterial effect of chitosan. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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