Metabolic adaptations in McArdle's disease and its mechanisms.

Autor: Santos, Pedro Henrique Silva, Rodrigues, Luis Felipe, Improta‐Caria, Alex Cleber, Voltarelli, Vanessa Azevedo
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Zdroj: Journal of Physiology; Mar2023, Vol. 601 Issue 6, p1051-1052, 2p
Abstrakt: Muscle glycogen unavailability and fat oxidation rate during exercise: Insights from McArdle disease. Keywords: glycogen and exercise; metabolism EN glycogen and exercise metabolism 1051 1052 2 03/17/23 20230315 NES 230315 The first records in the 1950s (McArdle, [2]) show that McArdle's disease affects one in every 100 000 individuals. Moreover, the increased MFO rate in McArdle's patients was reached in a significant higher workload compared to healthy controls, suggesting that these patients are better adapted to use fat as a substrate to sustain exercise. [Extracted from the article]
Databáze: Complementary Index