Two pairs of epimers and three undescribed diterpenoids from Pseudocaryopteris paniculata.

Autor: Zhang, Cheng-Gang, Chen, Ting, Yang, Jun-Jie, Mao, Xu-Dong, Chou, Gui-Xin
Předmět:
Zdroj: Natural Product Research; Apr2023, Vol. 37 Issue 7, p1074-1081, 8p
Abstrakt: A phytochemical investigation on the petroleum ether partition of the whole plant of Pseudocaryopteris paniculata, yield seven new compounds: one phytanes diterpenoid (2Z,6E,10E) 14-keto-2,6,10-trimethyl pentadeca-2,6,10-trien-1-carboxylic acid (1), five clerodane diterpenoids: paniculatins A-E (2, 3a/3b, 4a/4b), one abietane diterpenoid: ent-uncinatone (5), together with 12 known compounds. Their structures were elucidated on the basis of 1D and 2D Nuclear Magnetic Resonance (NMR_, Infrared Radiation (IR), and mass spectroscopic data. Compound 2, 5, and 11 showed weak selective cytotoxic activity of 11 human cancer cell lines. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index