Successful Treatment of Prolonged, Severe Coronavirus Disease 2019 Lower Respiratory Tract Disease in a B cell Acute Lymphoblastic Leukemia Patient With an Extended Course of Remdesivir and Nirmatrelvir/Ritonavir.

Autor: Ford, Emily S, Simmons, William, Karmarkar, Ellora N, Yoke, Leah H, Braimah, Ayodale B, Orozco, Johnnie J, Ghiuzeli, Cristina M, Barnhill, Serena, Sack, Coralynn L, Benditt, Joshua O, Roychoudhury, Pavitra, Greninger, Alexander L, Shapiro, Adrienne E, Hammond, Jennifer L, Rusnak, James M, Dolsten, Mikael, Boeckh, Michael, Liu, Catherine, Cheng, Guang-Shing, Corey, Lawrence
Předmět:
Zdroj: Clinical Infectious Diseases; Mar2023, Vol. 76 Issue 5, p926-929, 4p
Abstrakt: A patient with B-cell acute lymphoblastic leukemia (ALL) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had persistent, progressive pneumonia with viremia after 5 months of infection despite monoclonal antibodies, intravenous (IV) remdesivir and prolonged oral steroids. Twenty days of nirmatrelvir/ritonavir and 10 days of IV remdesivir led to full recovery. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index