| Autor: |
Gomes, Marilia Brito, Santos, Deborah Conte, Drummond, Karla, Pinheiro, André, Muniz, Luiza Harcar, Leal, Franz, Negrato, Carlos Antonio, Melo, Laura Nunes, Cobas, Roberta, Tannus, Lucianne Righeti Monteiro, Rodacki, Melanie, Zajdenverg, Lenita, Dantas, Joana Rodrigues, Corrêa-Giannella, Maria Lúcia Cardillo, Admoni, Sharon Nina, Santos, Daniele Pereirados, Guedes, Mariade Fatima, Dib, Sergio Atala, Filho, Celso Ferreirde Camargo Sallum, Pavin, Elisabeth João |
| Zdroj: |
Diabetology & Metabolic Syndrome; 2/23/2023, Vol. 15 Issue 1, p1-10, 10p |
| Abstrakt: |
Aims: To determine the prevalence of overweight/obesity and its relationship with metabolic syndrome (MS), fatty liver index (FLI), cardiovascular risk factors (CVRF), and diabetes-related chronic complications (DRCC) in adult patients with type 1 diabetes (T1D). Methods: This study was conducted in 14 Brazilian public clinics in ten cities, with 1,390 patients: 802 females (57.7%), 779 (56.0%) Caucasians, aged 33.6 ± 10.8 years, age at diagnosis, 16.2 ± 9.2 years, diabetes duration, 17.4 ± 9.2 years, and HbA1c 8.8 ± 2.0%. Results: Overall, 825 patients (59.4%) had normal weight, and 565 had overweight/obesity; (429 (30.9%) presented overweight and 136 (9.8%) presented obesity). After adjustments, overweight/obesity was associated with age, family history of overweight/obesity, total daily insulin dose, hypertension, adherence to diet, type of health care insurance, use of metformin, levels of C-reactive protein, triglycerides, uric acid and HDL-cholesterol. These patients also presented a higher prevalence of MS, FLI ≥ 60, and CVRF than patients without overweight/obesity. Overweight/obesity was not associated with DRCC and with HbA1c levels. Conclusions: Patients with T1D with overweight/obesity presented traditional risk factors for DRCC, cardiovascular diseases, MS, and non-alcoholic fatty liver disease; most of these risk factors are modifiable and can be avoided with interventions that prevent overweight/obesity. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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