The Cooperative Outcomes Group for ENT: A multicenter prospective cohort study on the effectiveness of medical and surgical treatment for patients with chronic rhinosinusitis

Autor: Witsell, David L., Stewart, Michael G., Monsell, Edwin M., Hadley, James A., Terrell, Jeffrey E., Hannley, Maureen T., Holzer, Susan Sedory
Zdroj: Otolaryngology-Head & Neck Surgery; Feb2005, Vol. 132 Issue 2, p171-179, 9p
Abstrakt: Objective: To assess outcomes for patients with chronic rhinosinusitis. Study design and setting: Prospective, multicenter study; 31 otolaryngologists enrolled 276 adult patients with chronic rhinosinusitis; patients completed surveys at 3-month intervals, and physicians provided clinical and treatment data. The primary outcome measure was the Chronic Sinusitis Survey-Duration(CSS-D). Results: One hundred seventeen adult patients completed 12-month follow-up. Most patients reported sinus symptoms lasting longer than 3 years(74%). Patients showed significant improvement(group P < 0.0001) in the CSS-D score at each follow-up interval. Baseline CSS-D(P < 0.0001), surgical intervention(P < 0.003), and Lund-McKay score(P < 0.04) were predictive of clinical success in regression analysis. Conclusions: Patients referred to an otolaryngologist have a severe sinus illness. Treatment by an otolaryngologist was associated with significant improvement in sinus-related symptoms. Significance: The study demonstrated the feasibility of multicenter outcome studies in chronic rhinosinusitis and generated testable hypotheses for future investigation. EBM rating: C. [Copyright &y& Elsevier]
Databáze: Complementary Index