MICEmi: A method to identify cognitive endophenotypes of mental illnesses.

Autor: Correa-Ghisays, Patricia, Vicent Sánchez-Ortí, Joan, Balanzá-Martínez, Vicent, Fuentes-Durá, Inmaculada, Martinez-Aran, Anabel, Ruiz-Bolo, Lara, Correa-Estrada, Paulina, Carlos Ruiz-Ruiz, Juan, Selva-Vera, Gabriel, Vila-Francés, Joan, Macias Saint-Gerons, Diego, San-Martín, Constanza, Ayesa-Arriola, Rosa, Tabarés-Seisdedos, Rafael
Předmět:
Zdroj: European Psychiatry; 2022, Vol. 65 Issue 1, p1-12, 12p
Abstrakt: Background Characterizing neurocognitive endophenotypes of mental illnesses (MIs) could be useful for identifying at-risk individuals, increasing early diagnosis, improving disease subtyping, and proposing therapeutic strategies to reduce the negative effects of the symptoms, in addition to serving as a scientific basis to unravel the physiopathology of the disease. However, a standardized algorithm to determine cognitive endophenotypes has not yet been developed. The main objective of this study was to present a method for the identification of endophenotypes in MI research. Methods For this purpose, a 14-expert working group used a scoping review methodology and designed a method that includes a scoring template with five criteria and indicators, a strategy for their verification, and a decision tree. Conclusions This work is ongoing since it is necessary to obtain external validation of the applicability of the method in future research. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index