Dana-Farber Cancer Institute Researcher Highlights Research in Leukemia (Mechanisms of response and resistance to combined decitabine and ipilimumab for advanced myeloid disease).

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Zdroj: Immunotherapy Weekly; 2/14/2023, p418-418, 1p
Abstrakt: Antineoplastics, Biotechnology, Cancer, Decitabine Therapy, Drugs and Therapies, Health and Medicine, Hematology, Immunologic Agents, Immunotherapy, Ipilimumab Therapy, Leukemia, Monoclonal Antibodies, Oncology, Pharmaceuticals, Yervoy Therapy, Antimetabolites Keywords: Antimetabolites; Antineoplastics; Biotechnology; Cancer; Decitabine Therapy; Drugs and Therapies; Health and Medicine; Hematology; Immunologic Agents; Immunotherapy; Ipilimumab Therapy; Leukemia; Monoclonal Antibodies; Oncology; Pharmaceuticals; Yervoy Therapy EN Antimetabolites Antineoplastics Biotechnology Cancer Decitabine Therapy Drugs and Therapies Health and Medicine Hematology Immunologic Agents Immunotherapy Ipilimumab Therapy Leukemia Monoclonal Antibodies Oncology Pharmaceuticals Yervoy Therapy A new study on leukemia is now available. Evidence of immune activation was only apparent following ipilimumab exposure, which altered CD4+ T cell gene expression, in line with ongoing T cell differentiation and increased frequency of marrow-infiltrating regulatory T cells. [Extracted from the article]
Databáze: Complementary Index