| Autor: |
Katic, M., Kahn, C. R. |
| Předmět: |
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| Zdroj: |
Cellular & Molecular Life Sciences; Feb2005, Vol. 62 Issue 3, p320-343, 24p, 3 Diagrams, 1 Chart, 1 Graph |
| Abstrakt: |
There are many theories of aging and parameters that influence lifespan, including genetic instability, telomerase activity and oxidative stress. The role of caloric restriction, metabolism and insulin and insulin-like growth factor-1 signaling in the process of aging is especially well conserved throughout evolution. These latter factors interact with each other, the former factors and histone deacetylases of the SIR family in a complex interaction to influence lifespan. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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