Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life.

Autor:	Nelson, Bryan S, Tierney, Camlin, Persaud, Deborah, Jao, Jennifer, Cotton, Mark F, Bryson, Yvonne, Coletti, Anne, Ruel, Theodore D, Spector, Stephen A, Reding, Christina, Bacon, Kira, Costello, Diane, Perlowski, Charlotte, Cruz, Maria Leticia Santos, Kosgei, Josphat, Majji, Sai, Yin, Dwight E, Jean-Philippe, Patrick, Chadwick, Ellen G, Team, for the IMPAACT P1115
Předmět:	HIV infections CLINICAL trials CONFIDENCE intervals CROSS-sectional method RESEARCH methodology HIGHLY active antiretroviral therapy CD4 lymphocyte count DESCRIPTIVE statistics RESEARCH funding DATA analysis software CHILDREN
Zdroj:	Clinical Infectious Diseases; 2/1/2023, Vol. 76 Issue 3, pe744-e747, 4p
Abstrakt:	We followed 54 infants with in utero HIV after initiating very early antiretroviral treatment. At weeks 24 and 48, ≥80% had CD4 ≥1500 cells/mm3 and CD4% ≥25%. Routine Pneumocystis jirovecii pneumonia prophylaxis in the first year of life may not be necessary for all very early treated infants. Clinical Trials Registration NCT02140255. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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