Scalable copper‐catalyzed preparation of imidazopyridinones from iodopyridinyl ureas.

Autor: Rugg, Kyle W., Balk, Regina C., Paolillo, Joshua M., Yerkozhanov, Dauzhan, Tampone, Thomas G., Holan, Martin, Buono, Frederic G., Reeves, Jonathan T.
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Zdroj: Journal of Heterocyclic Chemistry; Feb2023, Vol. 60 Issue 2, p335-340, 6p
Abstrakt: The efficient copper‐catalyzed construction of imidazopyridinones is described. Beginning from iodopyridinyl ureas, Ullmann coupling provides imidazopyridinones in good yield. Manufacturing by this process is described on 473 kg scale; the scope and limitations of substrates is also detailed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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