| Abstrakt: |
A series ofsiderophore-linked ruthenium catalysts were investigated for prodrugactivation, all of which displayed a combinative antibacterial effectwith the prodrug, whereas a representative example displayed littletoxicity against mammalian cell lines." Drugs and Therapies - Antibiotics Investigators publish new report on Drugs and Therapies-Antibiotics. Our news editors obtained a quote from the research from the Universityof York, "The use of small-molecule catalysts for prodrug activationwithin cells has shown promise in recent years, and here we investigatesiderophore-linked ruthenium catalysts for the activation ofantibacterial prodrugs within cells. [Extracted from the article] |
