A Case of Poorly Differentiated Synovial Sarcoma Arising in a Nasal Cavity Radiation Field: An Unusual Tumor in an Unusual Location.

Autor: Jobbagy, Soma, Bilek, Melissa, You, Bei, Shah, Maya, Jobbagy, Zsolt
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Zdroj: International Journal of Surgical Pathology; Feb2023, Vol. 31 Issue 1, p76-81, 6p
Abstrakt: Synovial sarcomas are high-grade soft tissue sarcomas of primitive mesenchymal origin which are defined by a pathognomonic t(X;18)(p11,q11) translocation, and which occur in pediatric and adult populations. Herein we report a case of a 33-year-old female with a history of nasopharyngeal carcinoma status post radiotherapy, presenting with a poorly differentiated synovial sarcoma of the nasal cavity arising in the radiation field. While the development of radiation-associated sarcoma is a known complication of radiotherapy, to date only 10 cases of synovial sarcoma have been reported to occur in previously irradiated tissues. Moreover, only 1 case of poorly differentiated synovial sarcoma involving the nasopharynx has been described. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index