Safety and Efficacy of Inpatient Pulmonary Rehabilitation for Patients Hospitalized with an AECOPD: Systematic Review and Meta-analyses.

Autor: Moecke, Débora Petry, Kai Zhu, Gill, Jagdeep, Brar, Shanjot, Petlitsyna, Polina, Kirkham, Ashley, Girt, Mirha, Chen, Joel, Peters, Hannah, Denson-Camp, Holly, Crosbie, Stephanie, Camp, Pat G., Petry Moecke, Debora, Zhu, Kai
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Zdroj: Annals of the American Thoracic Society; Feb2023, Vol. 20 Issue 2, p307-319, 27p
Abstrakt: Background: PR during hospitalization for AECOPD occurs during a period of disease instability for the patient, and the safety and efficacy of PR specifically during the hospitalization period has not been established.Objective: The purpose of this review is to determine the safety and efficacy of PR during the hospitalization phase for individuals with an AECOPD.Data Sources: Scientific databases were searched up to August 2022 for randomized controlled trials that compared in-hospital PR with usual care. PR programs commenced during the hospitalization and included a minimum of two sessions.Data Extraction: Titles and abstracts followed by full-text screening and data extraction were conducted independently by two reviewers. The intervention effect estimates were calculated through meta-analysis using a random-effect model.Synthesis: Twenty-seven studies were included (n=1317). The meta-analysis showed that inpatient PR improved the 6 minute walk distance by 105 meters (p<0.001). Inpatient PR improved the performance on the five repetition sit-to-stand test by -7.02 seconds (p=0.03). QOL as measured by the 5Q-5D-5L and the St. George's Respiratory Questionnaire was significantly improved by the intervention. Inpatient PR increased lower limb muscle strength by 33.35N (p<0.001). There was no change in length of stay. Only one serious adverse event related to the intervention was reported.Conclusion: This review suggests that it is safe and effective to provide PR during hospitalization for individuals with an AECOPD. In-hospital PR improves functional exercise capacity, QOL, and lower limb strength without prolonging the hospital LOS. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index