| Autor: |
Pham, Nguyen Kim Tuyen, Nguyen, Thi Diem Huong, Nguyen, Thi Mong Cam, Nguyen, Gia Dinh, Huynh, Cong Doan, Vo, Thi Nga, Nguyen, Thi Quynh Trang, Duong, Thuc Huy, Dang, Van Son, Huynh, Bui Linh Chi, Tran, Thi Ngoc Mai, Nguyen, Tan Phat |
| Předmět: |
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| Zdroj: |
Natural Product Research; Feb2023, Vol. 37 Issue 3, p455-461, 7p |
| Abstrakt: |
From the Lasianthus bidoupensis stems, two new compounds, including one new 9,10-anthraquinone, lasibidoupin A (1), and one new 6,7-benzocoumarin, lasibidoupin B (2), together with one known compound, 11-O-methyldamnacanthol (3) were isolated using chromatographic method. Their structures were determined by extensive HRMS, and NMR assignments. Compound 3 was reported for the first time from this species. New compounds (1 & 2) were tested for the cytotoxicity against three human cancer cell lines (MCF-7, HeLa, and NCI-H460) by SRB assay. As results, 1 & 2 exhibited significant cytotoxic activity against all cancer cell lines (IC50 ranged from 0.058 ± 0.003 to 0.177 ± 0.014 μM). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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