Mean Platelet Volume and Mean Platelet Volume/Platelet Count Ratio Are Predictors of Late-Onset Sepsis in Preterm Infants: A Case-Control Study.

Autor:	Guney Varal, Ipek, Dogan, Pelin, Acar Celik, Ezgi, Güler Kazancı, Elif
Předmět:	MEAN platelet volume PREMATURE infants PLATELET count SEPSIS GRAM-negative bacteria NEONATAL sepsis
Zdroj:	Fetal & Pediatric Pathology; Feb2023, Vol. 42 Issue 1, p44-54, 11p
Abstrakt:	Objective: Our aim was to assess mean platelet volume (MPV) and mean platelet volume to platelet count ratio (MPR) in the setting of late-onset sepsis (LOS) and their association with the type of bacteria causing LOS. Study design: The MPV and MPR levels were obtained at the onset of LOS and then assessed in intra/inter group analyses in preterm infants. Results: Overall, 136 preterm infants were enrolled. The MPV and MPR levels were higher during a LOS event (P < 0.001). A MPV cutoff of >9.2 was related with a sensitivity of 63% and a specificity of 73% for predicting LOS (P < 0.001). A MPR cutoff of >0.15 was related with a sensitivity of 88% and a specificity of 63% for predicting gram negative LOS (P < 0.001). Conclusion: Elevated MPV values and MPR ratios may be helpful in assessing LOS. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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