Spontaneous transient size reduction of a solitary pulmonary metastasis from a leiomyosarcoma.

Autor: Ito, Nao, Iizuka, Shuhei, Sasaki, Kanji, Otsuki, Yoshiro, Nakamura, Toru
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Zdroj: Surgical Case Reports; 1/26/2023, Vol. 9 Issue 1, p1-4, 4p
Abstrakt: Background: A solitary pulmonary nodule (SPN) poses a diagnostic challenge, which includes both a benign and malignant etiology. A size enlargement often indicates malignancy. We herein describe a case of a solitary pulmonary metastasis from a leiomyosarcoma that regressed transiently during follow-up. Case presentation: A 47-year-old woman presented with an SPN detected by follow-up computed tomography 7 years after surgery for a left forearm high-grade leiomyosarcoma. The nodule regressed spontaneously after an additional 6 months, and therefore, an inflammatory change was the most likely diagnosis at that time. However, the nodule enlarged again over the next 5 years. The growth rate led us to suspect a malignancy. A trans-bronchial biopsy was undiagnostic and a video-assisted thoracic surgery was planned. She underwent a wedge resection of the right lung, and a histopathological examination found it was a metastatic leiomyosarcoma. Conclusions: A pulmonary metastasis from a leiomyosarcoma could emerge as an SPN and reveal a subsequent transient size reduction. An SPN in patients even with a remote history of a soft tissue tumor should raise the possibility of metastasis, and periodic follow-up is essential even after the size reduction. [ABSTRACT FROM AUTHOR]
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