Effectiveness of monthly low dose emicizumab prophylaxis without 4‐week loading doses among patients with haemophilia A with and without inhibitors: A case series report.

Autor: Chuansumrit, Ampaiwan, Sirachainan, Nongnuch, Jaovisidha, Suphaneewan, Jiravichitchai, Tachit, Kadegasem, Praguywan, Kempka, Ketsuda, Panuwannakorn, Monratta, Rotchanapanya, Wannaphorn, Nuntiyakul, Thunyakorn
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Zdroj: Haemophilia; Jan2023, Vol. 29 Issue 1, p382-385, 4p, 2 Charts
Abstrakt: Effectiveness of monthly low dose emicizumab prophylaxis without 4-week loading doses among patients with haemophilia A with and without inhibitors: A case series report In conclusion, the monthly low-dose emicizumab prophylaxis of the whole vial at 1.05-1.66 mg/kg without loading dose showed effectiveness among patients with haemophilia A with and without inhibitor. Keywords: emicizumab; haemophilia A; inhibitor; loading dose; low dose EN emicizumab haemophilia A inhibitor loading dose low dose 382 385 4 01/27/23 20230101 NES 230101 Prophylaxis among patients with severe haemophilia A has clear efficacy to prevent bleeding episodes and subsequent sequelae of muscles and joints. Despite no patient included in this study reporting a zero annual bleeding rate, two of six included patients did achieve zero annual joint bleeding (33.3%). [Extracted from the article]
Databáze: Complementary Index
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