Wider perspectives: It's a changing world—The use of ABO‐incompatible plasma for resuscitating massively bleeding patients.

Autor: Yazer, Mark H., Díaz‐Valdés, José R., Triulzi, Darrell J., Cap, Andrew P.
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Zdroj: British Journal of Haematology; Feb2023, Vol. 200 Issue 3, p291-296, 6p
Abstrakt: If the clinical suspicion of haemolysis is high and the laboratory testing is suggestive, the patient's ongoing transfusion needs can be met with group O RBCs that are invulnerable to haemolysis from anti-A and anti-B, and AB-group- or ABO-group-identical plasma products. Measurement of haemolysis markers following transfusion of uncrossmatched, low-titre, group O+ whole blood in civilian trauma patients: initial experience at a level 1 trauma Centre. When these parameters are compared between injured group O recipients of LTOWB and non-group-O LTOWB recipients, no clinical or laboratory evidence for haemolysis was detected in adults[[47], [49]] and children.[[51]] Comparing haemolysis markers between the group O recipients to the non-group-O recipients is important to account for the baseline changes in these parameters that occur secondary to the trauma itself; the group O recipients are essentially the control group to which the magnitude of any changes in the haemolytic parameters amongst the non-group-O recipients are compared. Keywords: ABO; hemolysis; incompatible; plasma; transfusion; trauma; whole blood EN ABO hemolysis incompatible plasma transfusion trauma whole blood 291 296 6 01/23/23 20230201 NES 230201 Do not say, "Why were the old days better than these?". [Extracted from the article]
Databáze: Complementary Index
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