| Abstrakt: |
The use of sunscreens helps protect the skin against effects of ultraviolet rays emitted by the sun such as, oxidation, burns, and inflammation. These sunscreens are mostly made of several chemical molecules that can induce undesirable reactions. For that, we aimed by the current study to evaluate the UV absorption, antioxidative action and anti-inflammatory effects of three oils from seeds of Brassica rapa, Raphanus sativus as well as Cucurbita maxima for possible use as sunscreen. The results obtained indicate that the three oils showed more absorption in UVB than UVA where we find that Brassica oil induce a maximum absorption of 90% in UVB and 75% in UVA compared to sunscreen SPF 50. In addition, an important antioxidant activity was observed by DPPH assay with maxima more than 80%, the IC50 for oils were 1.2% for Brassica and Raphanus and was 1.5% for Cucurbita. Furthermore, the three oils exhibited an inhibitory effect on spleen cell proliferation reaching a maximum inhibition of 39%. These finding, for the first time, shed light on the UV-absorption properties of seed oil from Brassica, Raphanus and Cucurbita. These properties allow the development of a new sunscreen formulation using oils from these seeds for skin treatment and protection. [ABSTRACT FROM AUTHOR] |
