Phytochemical Composition, Antioxidant Potential and a-Amylase Inhibitory Activity of Different Extracts from Aaronsohnia pubescens (Desf.).

Autor: Kandouli, Chouaib, Leulmi, Zineb, Bahri, Laid, Oufroukh, Karima, Abdessemed, Ala, Mechakra, Aicha
Předmět:
Zdroj: Jordan Journal of Biological Sciences; Dec2022, Vol. 15 Issue 4, p697-707, 11p
Abstrakt: The medicinal plant Aaronsohnia pubescens is currently used in the algerian phytotherapy to treat several disorders. In order to investigate the potential influence of A. pubescens, six extracts were screened for their antioxidant and anti-amylase capacities. Antioxidant ability was evaluated by different assays as well as scavenging effect of free radicals (DPPH, ABTS, GOR and hydroxyl radical), metal chelating, reducing power, CUPRAC and total antioxidant capacity. Total phenolic and flavonoid contents in these extracts were also measured. Phenolic compounds in different extracts were identified using the HPLC-DAD analysis. The total phenolic contents of these extracts ranged from 70 to 335.9 mg GAE/g. Generally, the highest amounts of total phenolic and flavonoid contents were observed in ethyl acetate and n-butanol extracts, which may explain their strong antioxidant activity. All extracts demonstrated a significant inhibitory activity on a-amylase. Based on these findings, A. pubescens could serve as a source of natural compounds for oxidative damage and diabetes mellitus management. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index