An Overview of Ischemia--Reperfusion Injury: Review on Oxidative Stress and Inflammatory Response.

Autor: Güler, Mustafa Can, Tanyeli, Ayhan, Akdemir, Fazile Nur Ekinci, Eraslan, Ersen, Şebin, Saime Özbek, Erdoğan, Derya Güzel, Nacar, Tuncer
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Zdroj: Eurasian Journal of Medicine; 2022 Supplement, Vol. 54, pS62-S65, 4p
Abstrakt: Ischemia--reperfusion is a common health problem leading to several health conditions. The pathophysiology of ischemia--reperfusion is quite complex. Oxidative stress and inflammatory response contribute to ischemia-- reperfusion mechanisms. Various parameters like proinflammatory cytokines, reactive oxygen species, occur during ischemia--reperfusion . There are several ways to investigate these values through biochemical and histopathologic findings. Malondialdehyde, glutathione, myeloperoxidase, superoxide dismutase, interleukin 6, interleukin 1β, tumor necrosis factor alpha, caspase-3, nuclear factor-kappa β, and LC3B (micr otubu le-as socia ted protein light chain 3, LC3) can be evaluated among these indicators. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index