| Autor: |
Eržen, Nevenka Kožuh, Kužner, Jernej, Drobnič-Košorok, Marinka |
| Předmět: |
|
| Zdroj: |
Pflügers Archiv: European Journal of Physiology; Oct2000, Vol. 440 Issue 7, pr168-r170, 3p |
| Abstrakt: |
Clinical investigations of terbinafine indicate its high treatment activity against infections by several dermatophytes. Its efficiency was tested also in the treatment of microsporosis in cats. The distribution of terbinafine in cat’s plasma and hair is important for the identification of the drug efficiency. A fast and reliable reversed-phase high performance liquid chromatographic method with appropriate sample preparation has been developed. Reliability, good reproducibility and low detection limit (LOD 0.25 ng/ml) of the method enable determination of terbinafine in hair and also in plasma of cats infected with Microsporum canis treated by Lamisil® tablets. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink