| Autor: |
Dickey, Brittney L, Giuliano, Anna R, Sirak, Bradley, Abrahamsen, Martha, Lazcano-Ponce, Eduardo, Villa, Luisa L, Coghill, Anna E |
| Předmět: |
|
| Zdroj: |
Journal of Infectious Diseases; 1/15/2023, Vol. 227 Issue 2, p256-260, 5p |
| Abstrakt: |
Background Human papillomavirus (HPV)-related oropharyngeal cancer (OPC) incidence is increasing among men. Biomarkers that can identify oral HPV16/18 infections likely to persist, the obligate precursor for HPV-OPC, are needed. Methods We assessed the association between oral Epstein-Barr virus (EBV) and oral HPV16/18 persistence among 63 men in the HPV Infection in Men Study who tested positive for HPV16/18 at the baseline visit. Control of oral coinfections, including EBV, could serve as a biomarker of immune competence and the ability to control oral HPV. Results Detection of oral EBV was significantly associated with oral HPV16/18 ≥12-month persistence. Conclusions Detection of oral EBV deserves evaluation as a biomarker for oral HPV persistence and HPV-related OPC. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
