Intramedullary spinal cord metastasis of clear cell renal carcinoma in a Von Hippel-Lindau patient.

Autor: Holanda, Tiago S. F., Lopes Jr., Edson
Předmět:
Zdroj: Surgical Neurology International; 2022, Vol. 13, p1-6, 6p
Abstrakt: Background: Intramedullary spinal cord metastasis is uncommon and represents only 0.6% of all spinal tumors. Renal cell carcinoma is even less frequent in this group than in lung and breast cancer. Patients with Von Hippel-Lindau disease (VHLd) present spinal hemangioblastoma more frequently. Case Description: A 59-year-old female patient presented with medullary syndrome. There was a previous history of VHLd, with a cerebellar hemangioblastoma resection years ago. The radiological investigation showed a cervical intramedullary solid-cystic lesion. The patient has submitted a tumor resection, and a pathological and immunohistochemistry study confirmed clear cell renal carcinoma metastasis. Conclusion: In patients with VHLd, the presence of an intramedullary solid-cystic lesion may not represent always a hemangioblastoma. Other diagnostic possibilities must be evaluated, despite being epidemiologically less frequent. Inside the group of patients with VHLd, only a previous case of intramedullary spinal cord renal cell carcinoma was reported in the literature. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index