The collagen matrix dural substitute graft prevents postoperative cerebrospinal fluid leakage after ventriculoperitoneal shunt surgery in patients aged <1 year.

Autor: Masanori Sato, Tatsuki Oyoshi, Hirofumi Iwamoto, Natsuko Tanoue, Soichiro Komasaku, Nayuta Higa, Hiroshi Hosoyama, Hiroshi Tokimura, Satoshi Ibara, Ryosuke Hanaya, Koji Yoshimoto
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Zdroj: Surgical Neurology International; 2022, Vol. 13, p1-4, 4p
Abstrakt: Background: Cerebrospinal fluid (CSF) leakage is a common complication of ventriculoperitoneal shunt (VPS) and has the potential to induce shunt infection. Especially in infants and children, these are serious complications. DuraGen is a collagen matrix dural substitute used to reduce the risk of CSF leakage in various neurosurgeries. We report our VPS procedure with DuraGen for preventing postoperative CSF leakage in patients aged <1 year. Methods: We used DuraGen to prevent postoperative CSF leakage in six VPS surgeries. Antibiotic-impregnated shunt catheters and programmable valves with anti-siphon devices were also used in all cases. DuraGen was placed inside and atop the burr hole. All cases had an initial shunt pressure of 5 cmH2O. Fibrin glue was not used. Results: The patients underwent follow-up for a year after VPS surgery. There was no postoperative subcutaneous CSF collection or leakage after all six VPS surgeries. Furthermore, no postoperative shunt infections or DuraGeninduced adverse events were noted. Conclusion: We speculate that DuraGen has a preventive effect on postoperative CSF leakage in VPS cases aged <1 year. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index