| Autor: |
Silva de Carvalho, Tayana, Brasil, Alódia, Leão, Luana K. R., Braga, Danielle Valente, Santos-Silva, Mateus, Assad, Nadyme, Luz, Waldo Lucas, de Jesus O. Batista, Evander, de Nazareth Tavares Bastos, Gilmara, Matos Herculano Oliveira, Karen Renata, Wanderley Picanço Diniz, Domingos Luiz, Herculano, Anderson Manoel |
| Předmět: |
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| Zdroj: |
Food & Nutrition Research; 2022, Vol. 66 Issue 2022, p1-11, 11p |
| Abstrakt: |
Background: Açaí (Euterpe oleracea) has a rich nutritional composition, showing nutraceutical and protective effects in several organs. In this study, the effects of an açaí-enriched diet on motor performance, anxiety-like behavior, and memory retention were deeply investigated. Methods: Eight-week male Wistar rats were fed with an Euterpe oler acea (EO) pulp-enriched diet, an olive oil-enriched (OO) diet (polyunsaturated fatty acid [PUFA] fat control diet), or a chow diet for 31 days (28 days pre-treatment and 3 days during behavioral tests). Afterward, ani mals were submitted to a battery of behavioral tests to evaluate spontaneous motor behavior (open-field test), anxiety-like behavior (elevated plus maze and open-field test), and memory retention (step-down). Oxidative stress in the hippocampus was evaluated by a lipid peroxidation assay. Results: EO-enriched diet did not influence the body weight and food intake but increased the glucose plasmatic level after 31 days under this diet. However, a similar fat-enriched diet stimulated a marked weight gain and reduced the food intake, followed by changes in the plasmatic lipid markers. EO-enriched diet preserved the motor spontaneous performance, increased the exploration in the aversive environment (anxiolytic-like effects), and elevated the latency to step-down (improved memory retention). The EO-enriched diet also reduced the level of lipid peroxidation in the hippo campus. These positive effects of EO-enriched diet can greatly support the usage of this diet as a preventive therapy. Conclusion: Taken together, the current study suggests that Euterpe oleracea-enriched diet promotes anxiolytic- like effects and improves memory consolidation, possibly due to the reduced levels of lipid peroxidation in the hippocampus. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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