| Autor: |
Robbins, D. S., Belden, E. L., Hoffman, P. M., Fudenberg, H. H., Strelkauskas, A. J. |
| Předmět: |
|
| Zdroj: |
Scandinavian Journal of Immunology; Jun1982, Vol. 15 Issue 6, p563-566, 4p |
| Abstrakt: |
Human T-cell subsets, defined by active E rosette formation, were examined for their ability to produce leucocyte migration inhibitory factor (LIF) in response to mitogen or specific antigen. It was determined that T cells enriched for active rosette-forming (A+) cells produced LIF in response to concanavalin A, whereas T cells depleted of active rosette-forming (A-) cells did not. Similarly, A+ cells from a tuberculin-sensitive donor produced LIF in response to tuberculin purified protein derivative, whereas A- cells from the same donor failed to produce the mediator. Thus, T-cell production of LIF in humans appears to be restricted to those T cells capable of active rosette formation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Plný text