Neutralization of B.1.617.2 variant through antibodies elicited by ChAdOx1‐S, BBIBP‐CorV, and Gam‐COVID‐Vac in an Argentinean cohort.

Autor: Blanco, Sebastián, Aguilar, Juan Javier, Spinsanti, Lorena, Diaz, Adrián, Beranek, Mauricio, Rivarola, María Elisa, Fernández, Elmer, Mangeaud, Arnaldo, Konigheim, Brenda Salomé, Gallego, Sandra V.
Předmět:
Zdroj: Journal of Medical Virology; Jan2023, Vol. 95 Issue 1, p1-4, 4p
Abstrakt: Neutralization of B.1.617.2 variant through antibodies elicited by ChAdOx1-S, BBIBP-CorV, and Gam-COVID-Vac in an Argentinean cohort There is global increasing concern about the emergence of SARS-CoV-2 variants along with a decrease of vaccine effectiveness. The escape of B.1.617.2 variant from neutralization has been previously reported.[[4], [6]] Nonetheless, we also show that among individuals with IPV, those immunized with BBIBP-CorV presented NTAbs titers against ancestral WT-B.1 significantly lower than unvaccinated individuals (GMT 5.35 and 6.42, respectively; I p i < 0.001). Groups: (A) Unvaccinated and recovered from natural infection by SARS-CoV-2 wild type; (B) vaccinated with two doses of ChAdOx1-S; (C) vaccinated with two doses of BBIBP-CorV; (D) vaccinated with two doses of Gam-COVID-Vac. [Extracted from the article]
Databáze: Complementary Index