| Autor: |
Anbiyaiee, Amir, Ramazii, Mohammad, Bajestani, Siamak Soltani, Meybodi, Seyed Mohammadmahdi, Keivan, Mona, Khoshnam, Seyed Esmaeil, Farzaneh, Maryam |
| Zdroj: |
Clinical & Translational Oncology; Jan2023, Vol. 25 Issue 1, p1-9, 9p |
| Abstrakt: |
Cancer as a progressive and complex disease is caused by early chromosomal changes and stimulated cellular transformation. Previous studies reported that long non-coding RNAs (lncRNAs) play pivotal roles in the initiation, maintenance, and progression of cancer cells. LncRNA activated by TGF-β (ATB) has been shown to be dysregulated in different types of cancer. Aberrant expression of lncRNA-ATB plays an important role in the progression of diverse malignancies. High expression of LncRNA-ATB is associated with cancer cell growth, proliferation, metastasis, and EMT. LncRNA-ATB by targeting various signaling pathways and microRNAs (miRNAs) can trigger cancer pathogenesis. Therefore, lncRNA-ATB can be a novel target for cancer prediction and diagnosis. In this review, we will focus on the function of lncRNA-ATB in various types of human cancers. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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