Clinical symptoms associated with laboratory findings and placental histopathology in full-term, non-infected neonates born to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive mothers.

Autor:	Briana, Despina D., Papaevangelou, Vassiliki, Syridou, Garyfallia, Paparizou, Kleopatra, Siafakas, Nikolaos, Konstantinidou, Anastasia E., Malamitsi-Puchner, Ariadne
Předmět:	SARS-CoV-2 PERIPARTUM cardiomyopathy ASPHYXIA neonatorum NEWBORN infants PLACENTA
Zdroj:	Journal of Maternal-Fetal & Neonatal Medicine; Dec2022, Vol. 35 Issue 25, p8706-8709, 4p
Abstrakt:	This study comprehensively examines clinical symptoms, laboratory findings, and placental pathology in 40 cases of singleton full-term SARS-CoV-2 negative neonates. Their mothers, previously healthy, with uncomplicated pregnancies, were infected peripartum and presented COVID-19 symptoms of various severity. Neonates had predominately diarrhea, the yet unreported absent sucking reflex, elevated COVID-19 inflammatory and ischemia/asphyxia markers as serum ferritin, interleukin-6 and cardiac troponin-T, while placentas demonstrated mild vascular and/or inflammatory lesions. We hypothesize that the above placental lesions may be associated with transient perinatal hypoxia resulting in absent sucking reflex, as well as with inflammatory cytokines transfer causing diarrhea. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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