Hemadsorption: A New Therapeutic Option for Selected Cases of Bromazepam Intoxication.

Autor:	Mekeirele, Michaël, Verheyen, Silke, Van Lancker, Ruth, Wuyts, Stephanie, Balthazar, Tim
Předmět:	FLUMAZENIL BENZODIAZEPINES CIRRHOSIS of the liver INGESTION RESPIRATION
Zdroj:	Case Reports in Nephrology & Dialysis; 2022, Vol. 12 Issue 3, p163-166, 4p
Abstrakt:	Benzodiazepine ingestion is frequent in patients admitted to ICU for intoxications. Generally, a supportive approach by securing the airway, breathing, and circulation is sufficient. Flumazenil is a well-known antidote for benzodiazepines but does not influence its elimination. Following preclinical data, we applied for the first time in humans a hemadsorption filter in a patient with a bromazepam intoxication. This technique proved to be effective in eliminating bromazepam in a patient with CHILD-C cirrhosis. We conclude that hemadsorption is a viable option to reduce length of ICU stay or intubation in slow metabolizers without contraindications. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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