Viral Zoonotic Diseases of Public Health Importance and Their Effect on Male Reproduction.

Autor: Okeleji, Olabisi Lateef, Ajayi, Lydia Oluwatoyin, Odeyemi, Aduragbemi Noah, Amos, Victor, Ajayi, Hezekiah Oluwatobi, Akinyemi, Amos Olalekan, Nzekwe, Chibueze Samuel, Adeyemi, Johnson Wale, Ajayi, Ayodeji Folorunsho
Předmět:
Zdroj: Zoonotic Diseases (2813-0227); Dec2022, Vol. 2 Issue 4, p291-300, 10p
Abstrakt: Simple Summary: There exists an almost unavoidable relationship between humans and animals. Humans keep animals as pets and use some for food. However, one should note that disease-causing organisms such as viruses can be present in these animals and be transmitted to humans, thereby causing life-threatening sickness or negatively impacting fertility. This article presents the existing evidence on the effects of some communicable viral diseases on male fertility. Knowing that infertility is a major concern to couples and families and that viral diseases affect men of all ages and locations, the authors question whether or not these viral diseases contribute to the state of infertility in men. This will help men and the general populace understands the extent of the damage of viral diseases transmitted by animals to their reproductive function and possible infertility. We believe this review is of educational, scientific and societal value. Zoonotic diseases occur as a result of human interactions with animals with the inadvertent transmission of pathogens from one to another. Zoonoses remain a major cause of morbidity and mortality among human populations, as they have been a source of pandemics in human history. Viral zoonoses account for a significant percentage of pathogens of zoonotic sources, posing a huge risk to men's general health and fertility. This review identifies the existing knowledge on the effects of viral zoonotic diseases on male fertility. Evidence from reviewed articles showed that viral zoonotic diseases elicit an immune reaction that induces inflammatory mediators and impairs testicular functions such as spermatogenesis and steroidogenesis, leading to abnormal semen parameters that lead to subfertility/infertility. Although most zoonotic viruses linger in semen long after recovery, their presence in semen does not directly translate to sexual transmission. There is a need to further delineate the possible risk of the sexual transmission of these diseases. While a few of the viral zoonotic diseases discussed have been well-studied, there is a need to place attention on others so as to fully understand their effects on male reproduction and therefore take the right steps towards preserving male fertility. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index