| Autor: |
Steinbüchel, A., Schlegel, H. G. |
| Předmět: |
|
| Zdroj: |
Molecular Microbiology; Mar1991, Vol. 5 Issue 3, p535-542, 8p, 3 Diagrams, 2 Charts |
| Abstrakt: |
The Alcaligenes eutrophus genes for β-ketothiolase, NADPH-dependent acetoacetyl-CoA reductase and poly(β-hydroxybutyric acid) synthase (PHB synthase) which comprise the three-step PHB-biosynthetic pathway, were cloned. Molecular studies revealed that these genes are organized in a single operon. The A. eutrophus PHB-biosynthetic genes are readily expressed in other bacteria, and DNA fragments harbouring the operon can be used as a cartridge to confer to other bacteria the ability to synthesize PHB from acetyl-CoA. The biochemical and physiological capabilities of A. eutrophus for the synthesis of a wide variety of polyhydroxyalkanoates are discussed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Plný text