Biosensors for the Rapid Detection of Cardiovascular Biomarkers of Vital Interest: Needs, Analysis and Perspectives.

Autor: Abensur Vuillaume, Laure, Frija-Masson, Justine, Hadjiat, Meriem, Riquier, Thomas, d'Ortho, Marie-Pia, Le Borgne, Pierrick, Goetz, Christophe, Voss, Paul L., Ougazzaden, Abdallah, Salvestrini, Jean-Paul, Leïchlé, Thierry
Předmět:
Zdroj: Journal of Personalized Medicine; Dec2022, Vol. 12 Issue 12, p1942, 13p
Abstrakt: We have previously surveyed a panel of 508 physicians from around the world about which biomarkers would be relevant if obtained in a very short time frame, corresponding to emergency situations (life-threatening or not). The biomarkers that emerged from this study were markers of cardiovascular disease: troponin, D-dimers, and brain natriuretic peptide (BNP). Cardiovascular disease is a group of disorders affecting the heart and blood vessels. At the intersection of medicine, basic research and engineering, biosensors that address the need for rapid biological analysis could find a place of choice in the hospital or primary care ecosystem. Rapid, reliable, and inexpensive analysis with a multi-marker approach, including machine learning analysis for patient risk analysis, could meet the demand of medical teams. The objective of this opinion review, proposed by a multidisciplinary team of experts (physicians, biologists, market access experts, and engineers), is to present cases where a rapid biological response is indeed valuable, to provide a short overview of current biosensor technologies for cardiac biomarkers designed for a short result time, and to discuss existing market access issues. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index