| Autor: |
Yannick Munyeku-Bazitama, Folefack, Gervais T., Yambayamba, Marc K., Tshiminyi, Paul M., Kazenza, Benito M., Otshudiema, John O., Guinko, Noe Tondri, Umba, Moreau D., Mulumba, Anastasie, Baketana, Lionel K., Mukadi, Patrick K., Smith, Chris, Muyembe-Tamfum, Jean-Jacques, Ahuka-Mundeke, Steve, Makiala-Mandanda, Sheila |
| Předmět: |
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| Zdroj: |
Emerging Infectious Diseases; Jan2023, Vol. 29 Issue 1, p89-97, 9p, 1 Diagram, 3 Charts, 1 Map |
| Abstrakt: |
Serologic surveys are important tools for estimating the true burden of COVID-19 in a given population. After the first wave of SARS-CoV-2 infections, a household-based survey conducted in Kinshasa, Democratic Republic of the Congo, estimated ≥292 infections going undiagnosed for every laboratory-confirmed case. To ascertain the cumulative population exposure in Kinshasa after the second wave of COVID-19, we conducted a prospective population-based cross-sectional study using a highly sensitive and specific ELISA kit. The survey included 2,560 consenting persons from 585 households; 55% were female and 45% male. The overall populationweighted, test kit-adjusted SARS-CoV-2 seroprevalence was 76.5% (95% CI 74.5%-78.5%). The seroprevalence was 4-fold higher than during the first wave, and positivity was associated with age, household average monthly income, and level of education. Evidence generated from this population-based survey can inform COVID-19 response, especially vaccination campaign strategies in the context of vaccine shortages and hesitancy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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