Alternative Geometries for 3D Bioprinting of Calcium Phosphate Cement as Bone Substitute.

Autor: Blankenburg, Jennifer, Vinke, Johannes, Riedel, Bianca, Zankovic, Sergej, Schmal, Hagen, Seidenstuecker, Michael
Předmět:
Zdroj: Biomedicines; Dec2022, Vol. 10 Issue 12, p3242, 18p
Abstrakt: In the literature, many studies have described the 3D printing of ceramic-based scaffolds (e.g., printing with calcium phosphate cement) in the form of linear structures with layer rotations of 90°, although no right angles can be found in the human body. Therefore, this work focuses on the adaptation of biological shapes, including a layer rotation of only 1°. Sample shapes were printed with calcium phosphate cement using a 3D Bioplotter from EnvisionTec. Both straight and wavy spokes were printed in a round structure with 12 layers. Depending on the strand diameter (200 and 250 µm needle inner diameter) and strand arrangement, maximum failure loads of 444.86 ± 169.39 N for samples without subsequent setting in PBS up to 1280.88 ± 538.66 N after setting in PBS could be achieved. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index