| Autor: |
Gillespie, Brigid, Harbeck, Emma, Rattray, Megan, Sandy-Hodgetts, Kylie, Thalib, Lukman, Patel, Bhavik, Erichsen Andersson, Annette, Walker, Rachel, Latimer, Sharon, Chaboyer, Wendy |
| Zdroj: |
Wound Practice & Research; Dec2022, Vol. 30 Issue 4, p242-242, 1/4p |
| Abstrakt: |
Objectives: To estimate the worldwide incidence of surgical wound dehiscence (SWD) and associated factors in adult general surgical patients. Methods: A systematic review and meta-analysis of published studies in MEDLINE (Ovid), CINAHL (EBSCO), EMBASE (Elsevier) and the Cochrane Library from 1 January 2010 to 23 April 2021 was undertaken. Eligible cross-sectional, cohort and observational studies available in full and English text were included. Data extraction and quality appraisal were undertaken independently by three reviewers. The I² statistic was used to explore heterogeneity. Random effects meta-analytic models were used in the presence of substantial heterogeneity. Subgroup, meta-regression and sensitivity analyses were used to explore sources of heterogeneity. Publication bias was assessed using Hunter's plots and Egger's regression test. Results: Of 3,633 publications retrieved, 27 studies were included. Meta-analysis pooled data from 743,347 patients from 24 studies. The pooled 30-day cumulative incidence of SWD was 1% (95% CI 1% to 1%). SWD incidence was highest in hepatobiliary surgery, at 3% (95% CI 0% to 8%). Multivariable meta-regression showed SWD was significantly associated with duration of operation and re-operation (F [2,10] =7.93 p=.009), explaining 58.2% of the variance. Conclusions: 1% of general surgical patients develop SWD but this is likely an underestimate. Most studies predated the agreed global definition for SWD and measured it as a secondary outcome. Wider uptake of this definition will inform SWD surveillance and improve accuracy of reporting. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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