| Autor: |
Abd-Elsabour, Mohamed, Assaf, Hytham F., Abo-Bakr, Ahmed M., Alhamzani, Abdulrahman G., Abou-Krisha, Mortaga M., Al-Mutairi, Aamal A., Alsoghier, Hesham M. |
| Předmět: |
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| Zdroj: |
New Journal of Chemistry; 1/7/2023, Vol. 47 Issue 1, p131-139, 9p |
| Abstrakt: |
In this work, a green-electrochemical synthesis was applied to catechol oxidation (1) to o-benzoquinone (2) using cyclic voltammetry and potential controlled coulometry. Encouraging results were obtained in the presence of semicarbazide (3) as a nucleophile in an ethanol/phosphate buffer mixture (pH 7.0). The pH, number of cycles, and scan rate were studied. The results indicate that the generated o-benzoquinone (2) participates in a Michael addition reaction with nucleophilic hydrazide via the ECEC mechanism to form a new triazinone adduct. The obtained results showed that a novel heterocyclic triazinone (9) product functionalized with hydroxyl and amide groups had been synthesized with a 68% yield. After purification, the product has been characterized by IR, UV-visible, GC/MS, 1H, and 13C NMR. The green-electrochemical synthesis approach produced novel organics with excellent purities and yields while being environmentally friendly and free of hazardous reagents. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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