| Abstrakt: |
Objective: The aim was to assess craniofacial features through facial anthropometric and lateral cephalometry measurements of individuals with mucopolysaccharidosis (MPS) and compare them with individuals without MPS. Design: Cross-sectional study. Patients: A total of 14 individuals with MPS and 28 non-MPS age- and sex-matched were enrolled in this study. Methods: A clinical facial analysis to evaluate the soft tissues and cephalometric analysis that comprised linear and angular measurements were performed. The calculation of the method error suggested no systematic errors (p >.05). Random errors for linear and angular measurements were low (less than 0.5° and 1.6 mm). Chi-square test and independent t-test were performed. Results: Most individuals with MPS were dolichofacial, presented altered facial proportions with an increased anterior lower facial height (ALFH) and lip incompetence (all p <.05), when compared with non-MPS individuals. Six angular measurements (1s.Na, 1s.NB, FMA, IMPA, AFI, and Po.Or_Go.Me; all p <.05) were significantly increased among individuals with MPS, and two (1s.1i and Ba.N-Ptm.Gn, all p <.05) were significantly decreased among them. Four linear measurements were significantly increased among individuals with MPS (1s-NA, 1i-NB, S-UL, and S-LL; all p <.05) and five (PogN-Perp, Co-A, Co-Gn, Nfa-Nfp, and overbite; all p <.05) were significantly decreased among them. Conclusion: In summary, most individuals with MPS were dolichofacial with increased ALFH. Proclined upper and lower incisors, reduced nasopharyngeal space, and reduced overbite was also noted. [ABSTRACT FROM AUTHOR] |
