| Autor: |
Minocha, Anil, Mokshagundam, Sriprakash, Gallo, Steven H., Rahal, Paramvir Singh |
| Předmět: |
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| Zdroj: |
American Journal of Gastroenterology (Springer Nature); Oct1994, Vol. 89 Issue 10, p1797-1800, 4p, 2 Charts |
| Abstrakt: |
Objective: To study the association between gastrointestinal motility and Helicobacter pylori (HP) among patients with nonulcer dyspepsia (NUD). Methods: We examined the gastric emptying and orocecal transit times (OCTT) in patients with NUD who were colonized with Helicobacter pylori (n = 27). NUD was defined as dyspeptic symptoms for at least 3 months in the absence of gastrointestinal pathology as seen on endoscopy and ultrasound. Subjects with diabetes mellitus, thyroid disorder, or abdominal surgery except appendectomy were excluded. The HP-negative patients with NUD (n = 38) served as controls. Solid phase gastric emptying was assessed by radionuclide scintigraphy. OCTT was determined by measuring exhaled breath hydrogen upon administration of lactulose. Results: The two groups were similar with respect to age, sex, race, and history of smoking. Gastric emptying (t½) was 64.96 ± 3.61 min in the HP-negative and 61.0 ± 6.59 in the HP-positive group (p = NS). The OCTT was 130.9 ± 17.26 minutes in the HP-negative and 84.28 ± 11.07 in the HP-positive group (p = 0.03). There was no difference in the prevalence of nonhydrogen producers between the two groups. There was no correlation between gastric emptying and OCTT (p > 0.05). Conclusions: OCTT is faster among HP-positive patients with NUD than among HP-negative patients. However, gastric emptying is similar in the two groups. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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