| Autor: |
Eindhoven, G. B., Diercks, R. L., Richardson, F. J., van Raaij, J. J. A. M., Hagenaars, J. A. M., van Horn, J. R., de Wolf, J. Th. M. |
| Předmět: |
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| Zdroj: |
Transfusion Medicine; Feb2005, Vol. 15 Issue 1, p13-18, 6p |
| Abstrakt: |
Although blood transfusion has never been safer, there remains concern about adverse effects. We designed guidelines, the 6-8-10-Flexinorm, based on the conditions which are relevant to the decision to transfuse. To evaluate these new guidelines, we performed a case–control study in patients undergoing elective primary total hip replacement. The study consisted of two parts. In the first part, physicians were strongly encouraged to use the new guidelines; in the second part, only registration took place. During the first and second part of the study, the use of packed red cells (PRC) in Hospital A (study hospital) decreased from 1·1 ± 1·5 to 0·6 ± 1·2 and 0·3 ± 0·9 units, whereas in Hospital B (control), the use of PRC remained unchanged (1 ± 1·5, 1 ± 1·7 and 1 ± 2 units). In the prestudy groups, 43% of the patients in Hospital A were transfused compared to 45% in Hospital B. In the first and second part of the study, 27%, respectively, 14% of the patients in Hospital A were transfused compared to 40% in both periods in Hospital B. The new guidelines lead to a reduction in the use of allogeneic blood and a decrease in the number of patients transfused. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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